Which of the following medications is known for its genotoxicity?

Abacavir (Ziagen) is recognized for its genotoxic potential, which refers to its ability to cause damage to genetic information within a cell. This property is particularly significant when considering the drug's potential for adverse effects in patients, as genotoxicity can lead to mutations and may contribute to the development of cancer. In the context of abacavir, research has suggested that it can result in DNA damage, leading to sensitivity in certain patients, especially those with specific genetic markers.

Understanding the genotoxicity of medications is essential for healthcare professionals, especially in sterile compounding environments. It emphasizes the importance of handling such medications with care to minimize exposure, as well as the need for screening patients for genetic predispositions before initiating therapy with drugs known to exhibit these properties.