Which of the following is a High Risk compounding example?

The selection of using non-sterile components in creating sterile preparations is identified as a high-risk compounding example for several reasons. In the context of sterile compounding, any introduction of non-sterile materials increases the potential for microbial contamination. Sterile preparations are critical since they are introduced directly into the patient's bloodstream or other areas where any contamination could lead to severe infections or other complications.

High-risk compounding involves scenarios where there is a significant chance of contamination from the outset. This includes using non-sterile ingredients or manipulating sterile products in non-sterile environments, which poses a heightened risk to patient safety. To mitigate these risks, strict adherence to compounding guidelines and aseptic techniques is imperative.

In contrast, compounding hydration fluids, compounding piggyback solutions, and filling parenteral nutrition containers are typically considered lower risk when proper sterility measures and components are utilized—reflecting established practices in sterile compounding. However, these examples may still involve risks that need to be managed, especially if non-sterile components are inadvertently included.