Which of the following is an example of Low Risk compounding?

Compounding piggybacks in an ISO 5 laminar flow hood is an example of Low Risk compounding because it involves the preparation of sterile products under controlled conditions that minimize contamination. In this scenario, the use of an ISO 5 laminar flow hood ensures that the environment is free from particulate contamination, which is essential for maintaining the sterility of the compounded product. Additionally, Low Risk compounding typically includes the mixing of sterile solutions without the need for complex manipulations or extensive handling of items that could increase the risk of contamination.

The other scenarios involve aspects that may elevate the risk level. For instance, compounding TPN (Total Parenteral Nutrition) with automated devices is usually considered more complex and involves handling multiple components that could increase risk due to the intricate nature of parenteral nutrition formulations. Transferring volumes from ampules into final sterile containers involves multiple steps and the potential for cross-contamination, which moves this process beyond the Low Risk category. Lastly, using bulk drug containers may also signify a higher volume or complexity that can introduce increased risk factors not present in a low risk scenario.