Which characteristic is not associated with incompatibility?

Incompatibility in compounded sterile preparations can manifest in several ways, which often indicate that two substances should not be mixed. When assessing the characteristics associated with incompatibility, color change, hazy appearance, and precipitation are all signs that indicate a reaction is occurring between the components, leading to undesirable outcomes.

Color change is commonly observed when a drug interacts with another substance, signaling a chemical change. A hazy appearance often suggests the formation of a colloidal or suspended particle that should not be present in a properly compounded sterile product. Precipitation is a more definitive sign of incompatibility where solid particles form in a solution, indicating that the compounds are reacting unfavorably.

In contrast, increased solubility is not a characteristic associated with incompatibility. If two substances increase in solubility when mixed, this often suggests compatibility rather than incompatibility. In general, when substances are compatible, they should dissolve effectively without any adverse reactions. Therefore, recognizing the traits of incompatibility helps technicians ensure the safety and efficacy of compounded sterile products.