What is the frequency for media fill testing for high risk CSP personnel?

The correct frequency for media fill testing for high-risk Compounded Sterile Preparation (CSP) personnel is every 6 months. Media fill testing is a crucial component of aseptic process validation that ensures the competency of personnel in performing sterile compounding procedures. This testing simulates the preparation of a sterile product without an actual drug, allowing for the identification of any potential contamination introduced by the compounding staff.

High-risk CSPs, which involve products exposed to conditions that could lead to contamination, require more frequent testing to ensure continued compliance with aseptic techniques.

By performing media fill tests every 6 months, facilities can monitor and assess the staff's practices, maintaining the highest standards of safety and sterility in medication preparation. Keeping this schedule helps identify any lapses in technique that need to be addressed through retraining or corrective actions, thus ensuring patient safety.