What is the Beyond Use Dating for Medium Risk preparations when refrigerated?

Medium-risk compounded sterile preparations refer to those that involve multiple individual or small doses of sterile products combined to create a compounded sterile preparation. These preparations typically involve more complex manipulations or the use of multiple ingredients.

According to the guidelines set forth by the United States Pharmacopeia (USP), the Beyond Use Date (BUD) for medium-risk preparations stored in the refrigerator is indeed 9 days. This is based on the increased potential for microbial contamination due to the complexity of the preparation process, as well as the various handling steps involved.

It is crucial for technicians compounding these preparations to adhere strictly to these guidelines, as exceeding this BUD could lead to a compromise in patient safety due to the risk of contamination. Understanding BUD is essential for ensuring that compounded sterile preparations are both effective and safe for patient use.

This date is significant as it guides the safe dispensing and storage of compounded medications, helping to maintain the integrity and sterility of the products prepared.