How often should low and medium risk CSP personnel undergo media fill testing?

Low and medium risk compounded sterile preparation (CSP) personnel should undergo media fill testing every 12 months. This timeframe is established to ensure that personnel maintain their competency in aseptic techniques and that they are capable of producing sterile products without contamination.

Media fill testing involves simulating the compounding process using a microbiological growth medium instead of a drug product. This allows for an assessment of the compounding personnel's ability to maintain sterile conditions. Performing this test annually helps identify any potential issues with aseptic technique that may have developed over time, ensuring the ongoing safety and efficacy of compounded sterile products. Regular testing reinforces best practices in sterile compounding and complies with the standards set by regulatory authorities, helping to maintain a high level of patient safety.